![]() ![]() The materials appearing in Hazel or on our website are not comprehensive and are for general information purposes only. In the context of this agreement, “consequential loss” includes any consequential loss, indirect loss, real or anticipated loss of profit, loss of benefit, loss of revenue, loss of business, loss of goodwill, loss of opportunity, loss of savings, loss of reputation, loss of use and/or loss or corruption of data, whether under statute, contract, equity, tort (including negligence), indemnity, or otherwise.īecause some jurisdictions do not allow limitations on implied warranties, or limitations of liability for consequential or incidental damages, these limitations may not apply to you. or an authorized representative has been notified, orally or in writing, of the possibility of such damage. or the materials in Hazel, even if 412 Technology, Inc. or its suppliers be liable for any consequential loss suffered or incurred by you or any third party arising from the use or inability to use Hazel, our website, or any other services provided by 412 Technology, Inc. makes no warranties, expressed or implied, and hereby disclaims and negates all other warranties including, without limitation, implied warranties or conditions of merchantability, fitness for a particular purpose, or non-infringement of intellectual property, or other violation of rights. To the extent permitted by law, 412 Technology, Inc. Hazel and the materials in Hazel and on our website are provided on an ‘as is’ basis. This permission can be revoked at any time by deleting Hazel from your device. You give us permission to download and install updates to Hazel on your device in accordance with your privacy preferences. This license shall automatically terminate if you violate any of these restrictions or these Terms of Service, and may be terminated by 412 Technology, Inc. This constitutes the grant of a license, not a transfer of title. You may download Hazel, to view, use, and display the application on your mobile device for your personal use only. The intellectual property in the materials in Hazel and on our website are owned by or licensed to 412 Technology, Inc. Use Hazel or its associated services in such a way that may infringe the privacy, intellectual property rights, or other rights of third parties. Harvest, collect, or gather user data without the user’s consent or Use Hazel to send unauthorized advertising or spam Use Hazel or its associated services in violation of any applicable laws or regulations ![]() Use Hazel or its associated services to transmit or publish any harassing, indecent, obscene, fraudulent, or unlawful material Knowingly or negligently use Hazel or any of its associated services in a way that abuses or disrupts our networks or any other service 412 Technology, Inc. Transfer Hazel or any of its associated materials to another person or “mirror” the materials on any other server ![]() Remove any copyright or other proprietary notations from Hazel or any materials and software contained within Hazel or on our website Modify, copy, prepare derivative works of, decompile, or reverse engineer Hazel or any materials and software contained within Hazel or on our website These Terms of Service were last updated on 29 October 2021.īy using Hazel and our website, you warrant on behalf of yourself, any entity who you represent who has entered into these Terms of Service, and your users that you will not: Any changes to these Terms of Service will take effect immediately from the date of publication. Upon doing so, we will update this page and notify you through the app and/or the email address you provided when you created your account. We, 412 Technology, Inc., reserve the right to review and amend any of these Terms of Service at our sole discretion. Terms and Conditions including the Google Apps Terms of Service. If you access or download Hazel from (1) the Apple App Store, you agree to any Usage Rules set forth in the App Store Terms of Service and/or (2) the Google Play Store, you agree to the Android, Google Inc. If you do not agree with these Terms of Service, you are prohibited from further using the app, accessing our website, or using any other services provided by 412 Technology, Inc. When you create a Hazel account or use Hazel, you agree to abide by these Terms of Service and to comply with all applicable laws and regulations. These Terms of Service govern your use of Hazel, our website located at, and any related services provided by 412 Technology, Inc.
0 Comments
2/26/2024 0 Comments Death row records shirt yellow![]() ![]() Its league of emcees, invigorated by newcomers such as Nate Dogg, Tha Dogg Pound, RBX, The Outlawz, Kurupt, and The Lady of Rage, eschewed the more lyrical style of the East Coast for music that was wholly uncompromising in its directness. The militant politics and profoundly explicit lyrics, a reflection of the “ post-Reaganomics, crack-cocaine era that transformed South Central Los Angeles into a 1980s war zone ,” made Death Row an inescapable cultural fixture. Protégé Snoop Doggy Dogg’s Doggystyle debut, and the next four Death Row albums after it, garnered platinum-plus status. The Chronic did not disappoint, becoming a multi-platinum milestone that would define the G-funk sound and scope of everything thereafter. Interscope, an LA-based outfit run by Ted Field and Jimmy Iovine that was on the verge of going under, recognized the profits that could come from betting on music that made Tipper Gore’s blood boil and decided to distribute Dre’s long-awaited solo debut. Dre performing at The Brixton Academy in London, Britain, 1994 - Brian Rasic/Getty Images Parent company Godfather Entertainment was born, and Death Row finally had a stake in the game. As if foreshadowing the mayhem that was to come, the invitations were printed to resemble subpoenas. The public “springing” of the partnership occurred at a label rollout party hosted at famous Beverly Hills restaurant Chasen’s. With the guidance of Kenner, and with Knight overseeing negotiations, Harris invested $1.5 million as a silent partner in Death Row for a 50% share. At the time, Harris was imprisoned on drug and attempted murder charges, so it fell to his lawyer David Kenner, a top-flight attorney with Hollywood connections, to broker a deal with Knight. The money would come from Michael “Harry-O” Harris, one of LA’s biggest cocaine kingpins who legitimized his entrepreneurial image through various means, including producing Broadway play “Checkmates,” which gave Denzel Washington his start on the big stage. If the story is to be believed, then Death Row was in part funded by the extortion of the man responsible for “Ice Ice Baby.”Īssisted by SOLAR Records owner Dick Griffey, who offered the fledgling label an office and a studio in Hollywood, the Death Row enterprise had a space but desperately needed an infusion of cash. Vanilla Ice claims that Knight threatened to throw him off a hotel balcony if he didn’t sign over royalties that he supposedly lifted from one of Knight’s associates. Tasked with handling “business” affairs, Knight flexed his ability to extract royalties owed to black artists from record labels and white artists. after strong-arming their contracts from Eazy-E’s Ruthless Records (Eazy would later claim in a lawsuit that Knight and his posse threatened him with lead pipes and baseball bats ). Vowing to make it “the Motown of the ‘90s,” Knight co-founded Death Row Records with Dre and D.O.C. Enter rap music mogul Marion “Suge” Knight, an imposing 350-pound brute once called “the most feared man in hip hop.” A music biz tough guy and rap’s most notorious boogeyman, the Big Bad Wolf with a cigar had gotten his start in the industry working as a bodyguard for Bobby Brown before landing a position as D.O.C.’s manager. ![]() Dre and his partner, The D.O.C., decided to break out of the cycle of exploitation. Amid financial disputes and tired of labels ripping off black writers and performers, Dr. was raking in the cash, but the artists behind the music weren’t getting appropriately paid. It’s the oldest story in the book: N.W.A. Suge Knight smoking a cigar, 2002 - Gregg DeGuire/WireImage/Getty Images Cries of public morality from naysayers were squashed beneath lyrics that detailed the violence, drugs, sex, and police brutality of South Central Los Angeles to the tune of hundreds of thousands of record sales. Dre, the producer who engineered the direction of the group’s foul-mouthed and antagonistic debut Straight Outta Compton, a record that shoved aside radio play to connect with the streets. No one was more pivotal to this transformation than N.W.A., the seminal rap group that America had come to love and loathe. The music coming out of Compton in the late ‘80s forever altered the course of hip hop, both artistically and politically. A bastion of west coast gangsta rap, Death Row didn’t just sell “thug life” records it sold a lifestyle. At a time when the commercial pop-rap of Marky Mark and the Funky Bunch, Tone-Loc, and MC Hammer was dominating mainstream outlets, Death Row transformed hardcore rap into an international phenomenon. ![]() It’s a cautionary tale that speaks to the spoils of war and the dangers that unfold when money and power begin to stifle the music. The rise and fall of Death Row Records reads like a Greek epic, its larger-than-life characters and violent undercurrents the stuff of legend. Doom is the much-feared Judge of Toontown. Framed for the homicide, Roger solicits the help of boozing private eye Eddie. ![]() At the very least, all of the publicity surrounding the renovation is bringing renewed interest in the ride, Who Framed Roger Rabbit, and Disneyland. Judge Doom (formerly known as Baron Von Rotten) is the main antagonist of Disney/Touchstones 1988 hybrid film, Who Framed Roger Rabbit. Its the story of a man, a woman, and a rabbit in a triangle of trouble.Film tagline Who Framed Roger Rabbit is a 1988 fantasy-comedy film directed by Robert Zemeckis, produced by Steven Spielberg, and based on Gary K. The Evil Side of Comics and Hollywood Gina Misiroglu Michael Eury. They maintain that Jessica Rabbit was not a “damsel in distress,” and she held her own in both the film and the original ride. On the other hand, some fans are upset that the reboot ignores the original story. They like the idea of Jessica Rabbit as a private eye, and believe the new narrative better connects the ride to the surrounding land. Jessica Rabbit from Who framed Roger Rabbit by TsunaCosplay. Some people are happy that the classic attraction is getting an update. Who Framed Roger Rabbit Movie Clip 1 Roger has a drink. Jessica Rabbit Upskirt Shot In Who Framed Roger Rabbit This myth managed to spread like wildfire because the sheer nature of Who Framed Roger Rabbit sort of invites it anyway, given that it's. ![]() Jessica Rabbit is now more empowered-and far less scantily clad.ĭisney’s update of the ride is getting a lot of attention, both positive and negative. Therefore, she has been transformed into a trench-coat-wearing private investigator who uses her intelligence to solve a problem in Toontown. Disney is ostensibly making the changes because it believes the Jessica Rabbit character embodies the “damsel in distress” stereotype, which may be seen by some as insensitive. On the one hand, linking particular characters to mockingbirds reduces them to the level of animals. So over the course of the novel, killing mockingbirds is associated with the sinful, the pointless, and the cruel. Like killing a mockingbird, arresting Boo would serve no useful purpose, and harm someone who never meant anyone any harm. "Well, it'd be sort of like shootin' a mockingbird, wouldn't it?" (30.66-68)Īll Boo does is watch the neighborhood, leave trinkets for Jem and Scout, and protect them when they're attacked. Tate was right."Ītticus disengaged himself and looked at me. "Yes sir, I understand," I reassured him. ![]() ![]() I ran to him and hugged him and kissed him with all my might. ![]() Mockingbirds turn up once more in the book, when Scout is telling Atticus she understands about not dragging Boo into court.Ītticus looked like he needed cheering up. Or maybe it's the senselessness that's really key: killing Tom brought about no good and prevented no evil, just like shooting a mockingbird. Or maybe Tom's innocence of the crime he's accused of makes him similar to the mockingbird who does no harm to anyone. Maybe it's along the lines of "women and children first": those thought to be weak should receive special protection. Underwood says it's because of Tom's disability, though it's unclear why he thinks that makes a difference. Underwood may be trying to get through to even the stupidest residents of Maycomb, but his editorial also makes sure that every reader gets the connection: the mockingbird and Tom are in the same class of beings. He likened Tom's death to the senseless slaughter of songbirds by hunters and children, and Maycomb thought he was trying to write an editorial poetical enough to be reprinted in The Montgomery Advertiser. Underwood simply figured it was a sin to kill cripples, be they standing, sitting, or escaping. Underwood didn't talk about miscarriages of justice, he was writing so children could understand. Underwood's editorial after the death of Tom Robinson doesn't mention mockingbirds by name, but it does have a similar message. ( The same could be said for cows, but hamburgers are so tasty, while mockingbirds presumably aren't.) But is this lesson so important in itself that it's worth putting it front and center on the cover of the book? So, mockingbirds are harmless, innocent creatures, and killing them is wrong, because they don't hurt anyone. That's why it's a sin to kill a mockingbird." (10.7) They don't eat up people's gardens, don't nest in corncribs, they don't do one thing but sing their hearts out for us. "Mockingbirds don't do one thing but make music for us to enjoy. That was the only time I ever heard Atticus say it was a sin to do something, and I asked Miss Maudie about it. Shoot all the bluejays you want, if you can hit 'em, but remember it's a sin to kill a mockingbird." "I'd rather you shot at tin cans in the back yard, but I know you'll go after birds. Atticus won't teach them how to shoot, but he does give them one rule to follow. They first appear when Jem and Scout are learning how to use their shiny new air rifles. ![]() The title of the book is To Kill a Mockingbird, so we're thinking that mockingbirds must be important. (Click the symbolism infographic to download.) 2/26/2024 0 Comments Security finance bank![]() Through securities, capital is provided by investors who purchase the securities upon their initial issuance. A disadvantage of bank loans as a source of financing is that the bank may seek a measure of protection against default by the borrower via extensive financial covenants. They may offer an attractive alternative to bank loans - depending on their pricing and market demand for particular characteristics. Securities are the traditional method that commercial enterprises use to raise new capital. For example, private investment pools may have some features of securities, but they may not be registered or regulated as such if they meet various restrictions. A country's regulatory structure determines what qualifies as a security. The company or other entity issuing the security is called the issuer. derivatives (e.g., forwards, futures, options, and swaps).equity securities (e.g., common stocks).debt securities (e.g., banknotes, bonds, and debentures).Securities can be broadly categorized into: In the United States, a "security" is a tradable financial asset of any kind. In the United Kingdom, the Financial Conduct Authority functions as the national competent authority for the regulation of financial markets the definition in its Handbook of the term "security" applies only to equities, debentures, alternative debentures, government and public securities, warrants, certificates representing certain securities, units, stakeholder pension schemes, personal pension schemes, rights to or interests in investments, and anything that may be admitted to the Official List. They include shares of corporate stock or mutual funds, bonds issued by corporations or governmental agencies, stock options or other options, limited partnership units, and various other formal investment instruments that are negotiable and fungible. Certificates may be bearer, meaning they entitle the holder to rights under the security merely by holding the security, or registered, meaning they entitle the holder to rights only if they appear on a security register maintained by the issuer or an intermediary. Securities may be represented by a certificate or, more typically, they may be "non-certificated", that is in electronic ( dematerialized) or " book entry only" form. ![]() In some jurisdictions it includes some instruments that are close to equities and fixed income, e.g., equity warrants. In some jurisdictions the term specifically excludes financial instruments other than equities and fixed income instruments. In some countries and languages people commonly use the term "security" to refer to any form of financial instrument, even though the underlying legal and regulatory regime may not have such a broad definition. The term commonly refers to any form of financial instrument, but its legal definition varies by jurisdiction. A security is a tradable financial asset. 2/26/2024 0 Comments Cadillac crossover concept![]() With even the Escalade coming in a hybrid version, Cadillac is making a strong play against its Japanese (i.e., Lexus) competitors. The other note of significance is how closely GM is tying its luxury brand to social responsibility. Whether it winds up with an E-Flex drivetrain right off the bat is debatable, and unlikely, but we'd be surprised if a production version of this car doesn't show up sometime relatively soon. ![]() Today at the Detroit Auto Show, GM unveiled another version of the platform, and quite possibly the best one yet: The Cadillac Provoq.Why it Matters The Provoq is one of the most production-ready concepts we've seen, and with all the rumors of a BRX small crossover, we're guessing that this is a close preview of that vehicle. Want to stay up to date on Cadillac’s surge into an all-electric future? Then make sure to subscribe to Cadillac Society for more future Cadillac product news, and 24/7 Cadillac news coverage.What it Is Cadillac Provoq Concept Preview – 2008 Detroit Auto Show: We’ve heard a lot about GM’s E-Flex platform, the series hybrid that underpins the Chevrolet Volt and Opel Flextreme concept cars shown last year in Detroit and Frankfurt. This may be revealed in short order, however, as the electric Cadillac crossover is expected to debut during the 2023 calendar year as a 2024 model year vehicle. It’s currently unclear what nameplate this vehicle will wear, but the luxury marque has filed to trademark Lumistiq, Ascendiq, Vistiq, and Optiq for use on future electric models. This model may also incorporate rear-wheel steering for increased maneuverability, as evidenced by a different set of spy shots. Ultium batteries and Ultium Drive motors will deliver the power. The forthcoming electric Cadillac crossover will ride on a longer variant of the BEV3 architecture that underpins the Lyriq. However, the curved screen panel doesn’t look like it’s wide enough to incorporate both the infotainment cluster as well as the center infotainment screen, though the finer details are difficult to make out here. ![]() While the image isn’t entirely clear, the interior appears to feature a cockpit configuration similar to that of the Lyriq. A tow hitch receiver also seems to be visible below the rear bumper cover.Īlso of note are chrome window surrounds and the flush-mounted door handles, similar to those of the Lyriq. A short spoiler hangs over the rear glass, while also integrating a center high-mounted stop lamp (CHMSL). The rear end seems to feature a set of vertical tail lamps with elements tracing the side of the vehicle’s D-pillars. Additionally, we can see a sleek shark-fin antenna affixed to the roof, just ahead of the liftgate. The first pane appears to be capable of opening, while the other two are likely fixed in place. However, this prototype clearly has a longer dash-to-axle ratio than the XT6, enabling a more cab-rearward configuration.Īnother angle reveals the electric Cadillac crossover’s glass roof, which sports a three-pane layout. The most readily discernable factor is the size of this electric Cadillac crossover, which appears to have a similar exterior footprint as the current Cadillac XT6. Unfortunately, the zebra-like pattern on this particular vehicle’s camo make it difficult to discern the lines. And now, we caught the upcoming EV testing once again, revealing more key details about its interior and exterior design. ![]() Shortly thereafter, our spies caught the model undergoing testing. The upcoming model is far enough along in the development process to warrant prototype testing, as Cadillac Society was first to report back in February. An electric Cadillac crossover that will slot above the Lyriq is on the way. 2/26/2024 0 Comments Elemental spirits![]() The Law required people to do certain things in order to approach God, but Christ removed any need for an intermediary. In Colossians 2:8, Paul is telling believers that when they adhere to the Law (to any degree), they are CHOOSING to become enslaved once more, when Christ has indeed SET THEM FREE. 2:13-15), and gives us access to God (Eph. Jesus (by His life, death, and resurrection) not only paid our debt and gave us eternal life in Himself, but also “disarmed the rulers and authorities and put them to open shame, by triumphing over them in him” (Col. Under the Law, humans are dead, condemned, and enslaved. The main point that Paul is getting at, however, is that believers are ALIVE in Christ! Our standing in Christ is completely different from our standing under the Law. Um, what? This is a new thought for me, and my guess is it probably is for you too. Look at what Galatians 3:19 says about the relationship between angels and the Law: “Why then the Law? It was added because of transgressions, until the offspring should come to whom the promise had been made, and it was put in place through angels by an intermediary.”Īccording to Scripture, the Law was put in place by angels. ![]() How exactly are we to understand the term “elemental spirits?” The Greek word “stoicheia” (used here in Colossians 2:8 as well as in Colossians 2:20, Galatians 4:3, and Galatians 4:9) is translated both as “elemental spirits” and “elemental principles.”Īccording to Oxford Biblical Studies Online, the most common way to understand these elemental spirits is as angels.īut why would angels want to take us captive? Aren’t they the good guys? In Colossians 2:8, Paul charges believers to not be taken captive by philosophy and empty deceit, “according to human tradition, according to elemental spirits of the world, and not to Christ.” 2/26/2024 0 Comments Music for imovie videos![]() Step 2 Click the " down arrow" on the top, locate the Amazon Music files, and click " Imported Selected" to upload Amazon Music songs to iMovie. Step 1 Open a video project or create a new one. In this part, we will show you how to add Amazon Music to iMovie for Mac. IMovie supports to load audio files in M4A, MP3, WAV, and AIFF formats, so the converted MP3-Format of Amazon Music is able to add to iMovie of course. Tips: After downloading Amazon Music to Mac via TuneBoto, you can find out the well-recorded Amazon songs in plain music format by clicking the " Converted" section, or directly going to the output path you previously set. Tap the button " Convert" and TuneBoto will start downloading Amazon Music songs immediately. Then TuneBoto will analyze and list the music you want and tap " Add". You can choose a preferred playlist on the main interface, and tap the " Click to add" icon. Webplayer mode: Go to Amazon Music web player. ![]() Then pick up the songs you want to use in iMovie and click " Add". Drag it to TuneBoto's interface or copy its link to the parse box. Tap the " Settings" tab, select output format, bit rate, sample rate, output path, and so on.Īpp mode: Select one playlist you want. Step 2 Select MP3 as the Output Format for iMovie BGM After choosing the mode, you need to log into your Amazon Music account. The former can download Amazon Music up to Ultra HD at 5X speed and the latter can download Amazon Music up to HD at 10X speed. Step 1 Select One Download Mode And Log In Amazon Music on Macĭownload and launch TuneBoto on a Mac and there will be two download modes for you to choose from: Amazon Music App and Amazon Music Webplayer. And here you will need: an Amazon Music Unlimited or Prime Music account, TuneBoto Amazon Music Converter, and a Mac computer. Next, we will show you a simple way to download Amazon Music to iMovie for video editing. Thankfully, this post includes a powerful audio recorder used to download both Amazon Music Unlimited and Prime Music to MP3, and a quick instruction to add converted songs from Amazon Music to iMovie. That means, music from streaming platforms, like Amazon Music, are not permitted. But in reality, it's not that straightforward - only audio files stored on your device are available to be imported to iMovie. To make a better video, you'll need to add some background music into your video to heighten atmosphere. It's a free and intuitive video maker for Mac users, and the latest version requires OS X 10.14.6 or later. When creating a project, editing clips, adding effects or music, iMovie always provides excellent movie making tools that meet demand. ![]() One of the best video editing software included in Apple devices must be iMovie. This article shows how to add Amazon Music songs to Apple iMovie on macOS 10.14 to 13 Ventura. Import Amazon Music to iMovie - Add Amazon Music to Video Clip 2/25/2024 0 Comments Lyrical lemonade wallpaper faze![]() 680x1209px Aesthetic Taylor Swift Lyrics Evermore, Taylor Swift Lyric Phone HD phone wallpaper.1000x1000px Sleepy Hallow – 2055 Lyrics, sleepy hallow 2055 HD phone wallpaper.4136x3072px Water, Food, Pepsi, Fresh, Lemonade HD wallpaper.750x1332px Lyrical Lemonade Iphone HD phone wallpaper.4000x2694px Lemonade, drink, lemon, holiday, summer HD wallpaper.Christian lyrics, Worship lyrics, Christian song lyrics, Oceans Hillsong HD phone wallpaper 843x1500px Taylor Swift Folklore Quotes, Taylor Swift Lyric HD phone wallpaper. ![]() 1000x1000px Kidd Keo – Kamata Lyrics HD phone wallpaper.4128x2322px with Arctic Monkey Lyrics (), Arctic Monkeys HD wallpaper.899x899px Deadsquad Lyrics, Songs, and Albums HD phone wallpaper.1200圆75px Dark Bts Aesthetic, BTS Lyrics HD wallpaper.1487x836px Most Relatable Lyrics From Taylor Swift's “evermore” HD wallpaper.1920x1080px GAL SUN LYRICS, shooter movie HD wallpaper.1200x940px Master – Quit Pannuda Lyric Song, master vijay sad HD wallpaper.Bts lyrics, Bts, Bts lyric HD phone wallpaper 1080x1920px BTS lyrics quotes / / life goes on.2400x2400px Pink Lemonade HD phone wallpaper.800x798px Life's Lemonade, lemonade, lemons, life, moral, sugar, funny, water HD wallpaper.Taylor swift lyrics, Taylor swift lyric quotes, Taylor lyrics, Taylor Swift Lyric Phone HD phone wallpaper 1080x1920px Taylor Swift's Lyric Phone Lock Screen.3840x2400px Happy Birtay Lyric,, pink neon lights, Lyric name, creative, Lyric Happy Birtay, Lyric Birtay, popular american female names, with Lyric name, Lyric HD wallpaper.752x1608px Lyrical Lemonade, cole bennett HD phone wallpaper.1000x1000px Dewa 19 – Dewi Lyrics HD phone wallpaper.Taylor swift lyrics, Taylor swift, Taylor lyrics, Taylor Swift Lyric Phone HD phone wallpaper 736x1104px about BEYONCÉ, Beyonce Lemonade HD phone wallpaper.1920x1080px Lil Skies, lyrical lemonade HD wallpaper.1000x1000px Seedhe Maut – 101 Lyrics HD phone wallpaper.Taylor swift lyrics, Taylor swift, Taylor swift, Lyric Laptop HD wallpaper Bts lyrics, Bts lyric, Bts lyrics quotes HD phone wallpaper 720x1280px Lockscreen Taylor Swift Folklore Lyrics, Taylor Swift Lyric Phone HD phone wallpaper.971x971px BoyWithUke – Toxic Lyrics, toxic boywithuke HD phone wallpaper.1920x1080px Made a Lyrical Lemonade : LyricalLemonade, cool summer lemonade HD wallpaper.1280x720px NO FARMER NO FOOD LYRICS NAV BENIPAL Lyrics Over A2z, No Farmers No Food HD wallpaper.1024x768px Taylor Swift Lyrics HD wallpaper.Bts lyrics quotes, Bts lyric, Bts HD phone wallpaper 1920x1080px Lyrics Taylor Swift, Lyric Laptop HD wallpaper.Taylor swift lyrics, Taylor swift, Taylor, Lyric Laptop HD wallpaper 1920x1080px TLGAD Lyrics - Taylor Swift.1080x1920px Formation Lyrics, Lemonade, Beyonce Lemonade HD phone wallpaper.Bts quotes, Bts lyrics, Song lyrics HD phone wallpaper 1080x1920px Life Goes On - BE Song Lyrics in 2021.Lemonade Juice, Lemonade and Jolteon Lemonade, Lemon Juice HD wallpaper 1280x720px LEGEND Song Lyrics, sidhu moose wala graphy HD wallpaper.1024x768px Taylor Swift Lyrics, Lyric Laptop HD wallpaper.taylor swift lyrics, taylor swift, lyrics, Taylor Swift Lyric Phone HD phone wallpaper 1080x1920px Taylor Swift lyrics ideas.Taylor swift lyrics, Taylor lyrics, Taylor swift, Lyric Laptop HD wallpaper 1440x900px Taylor swift the lakes laptop.1280x720px lyrical lemonade aesthetic HD wallpaper.Taylor swift lyrics, Taylor swift song lyrics, Taylor swift lyric quotes HD phone wallpaper 1080x1920px Taylor Swift's Lyric Phone Lock Screen in 2020.1280x720px Lyrical, vitthal mauli HD wallpaper.1024x1024px Lyrical Lemonade HD phone wallpaper.1920x1080px lyricallemonade: Lyrical Lemonade, lyrical lemonade computer HD wallpaper.IPad 3, iPad 4, iPad Air, iPad iPad, iPad Mini 2, iPad Mini 3, iPad Mini 4, 9.7" iPad Pro: 2048x1536, 1536x2048 IPhone 14 Pro Max, iPhone 15 Plus, iPhone 15 Pro Max: 1290x2796 IPhone 12 Pro Max, iPhone 13 Pro Max, iPhone 14 Plus: 1284x2778 IPhone Xs Max, iPhone 11 Pro Max: 1242x2688 IPhone X, iPhone Xs, iPhone 11 Pro: 1125x2436 IPhone 6 plus, iPhone 6s plus, iPhone 7 plus, iPhone 8 plus: 1242x2208 IPhone 6, iPhone 6s, iPhone 7, iPhone 8: 750x1334 IPhone 5, iPhone 5s, iPhone 5c, iPhone SE: 640x1136 IPhone: iPhone 2G, iPhone 3G, iPhone 3GS: 320x480 2/25/2024 0 Comments Molecular diagnostics industryMoreover, this regulatory loophole establishes a far-from-level playing field for test manufacturers, as some widely used tests that have been reviewed and approved by Health Canada, such as Prosigna’s NanoString and Myriad’s EndoPredict prognostic tests for early-stage breast cancer, compete on the Canadian market with tests that have bypassed such review, like Oncotype Dx. But growing commercial interest in molecular diagnostics calls this approach into question. In the past, such tests were developed in specialized hospital laboratories they were not regulated as medical devices and were distributed to patients as a health service. However, manufacturers can avoid this regulatory approval process by using the laboratory-developed test loophole. They are subject to premarket review by Health Canada to evaluate evidence of their safety and efficacy. But these 3 tests were neither evaluated nor approved by Health Canada.ĭiagnostics developed as “test kits” and sold to laboratories, hospitals and clinics are considered to be in vitro diagnostics devices under Medical Devices Regulation in accordance with the federal Food and Drugs Act. Oncotype Dx - which offers women with early-stage invasive breast cancer information about their likely response to chemotherapy and the chance of recurring cancer - is reimbursed in BC, Alberta, Saskatchewan, Ontario, Quebec and Newfoundland. 3 In Canada, many molecular diagnostics are covered by provincial health plans: for example, Harmony and Panorama, noninvasive prenatal tests that screen for common fetal trisomies, are covered for high-risk pregnancies in Ontario, British Columbia and the Yukon. ![]() The global molecular diagnostics market was estimated to be worth US$7.3 billion in 2017. Molecular diagnostics increasingly play a pivotal role in control of infectious disease, diagnosis of hereditary diseases and aspects of oncology. In the interests of the nation’s health, it should. Regulators in Australia, the United States and Europe have made efforts to close this “gaping regulatory loophole,” 2 but Health Canada has not indicated that it plans to do the same. Absent regulation as medical devices, the only controls on test performance are laboratory regulation and accreditation, which are heterogeneous and sometimes flawed and do not necessarily include assessment of test validity, safety and efficacy. Such tests are not subject to Canada’s statutory regulation of medical devices for safety and efficacy, but they are widely used in Canada’s health care system. The recent expansion of the molecular diagnostics industry has revealed weaknesses in the regulatory system for all laboratory-developed tests. These devices are diagnostic tests produced by a company in its own clinical laboratories and marketed as commercial services to health care providers who send samples to those laboratories for analysis “in house.” Some laboratory-developed tests may also be developed by public clinical laboratories and offered to local clients. ![]() 1 Yet an important subset of medical devices remains outside the purview of this regulatory overhaul: laboratory-developed tests. Health Canada can show leadership in the regulation of laboratory-developed tests, by building on the efforts of other jurisdictions, just as it has led the way in drug and device data transparency.Īn international exposé of flawed regulations for medical implants prompted Canada’s health minister to announce sweeping changes to the regulation of medical devices. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |